Salicin, also known as willow alcohol and salicin, has the formula C13H18O7. It is widely found in the bark and leaves of many willow and poplar plants, for example, the bark of purple willow can contain up to 25% salicin. It can be made by chemical synthesis. Salicinogen and salicylic acid can be found in urine 15-30min after oral administration, therefore, it has antipyretic, analgesic and anti-inflammatory, anti-rheumatic effects. Because such transformation is not constant, thus its therapeutic value is lower than that of salicylic acid. It also has a bitter stomachic and local anesthetic effect. It can also be used as biochemical reagent. It is wise to choose China Active Salicin. We are Active Salicin Factory; Active Salicin Manufacturer; Active Salicin Factories.
Salicin is white crystal; bitter taste; melting point 199-202℃, specific rotation [α]-45.6° (0.6g/100cm3 anhydrous ethanol); 1g soluble in 23ml water, 3ml boiling water, 90ml ethanol, 30ml 60° ethanol, soluble in alkali solution, pyridine and glacial acetic acid, insoluble in ether, chloroform. The aqueous solution shows neutral to litmus paper. No free phenolic hydroxyl group in the molecule, belongs to the phenolic glycosides. Hydrolyzed by dilute acid or bitter almond enzyme, it can produce glucose and salicyl alcohol. The molecular formula of salicyl alcohol is C7H8O2; it is a rhomboidal colorless needle crystal; melting point 86~87℃; sublimation at 100℃; soluble in water and benzene, easily soluble in ethanol, ether and chloroform; red color when met with sulfuric acid.
Salicin has antipyretic and analgesic effects, and was used in the treatment of rheumatism in the past, but has been replaced by other drugs. Because it can produce salicylic alcohol after hydrolysis, it can be easily oxidized to produce salicylic acid, so it was once the main source of synthetic salicylic acid drugs, and now the pharmaceutical industry has adopted the synthetic method to manufacture salicylic acid.
Salicin, an anti-inflammatory ingredient, also known as Willowbark extract, has anti-inflammatory properties that are a perfect substitute for salicylic acid, which causes skin irritation.
The efficacy of salicin
The efficacy of salicin: Salicin is an anti-inflammatory agent made of willow bark, which is metabolized by the body into salicylic acid. According to the Wikipedia description, it is similar in nature to aspirin and is traditionally used to heal wounds and muscle pain. Although the conversion of salicin to salicylic acid in the human body requires enzymes, topical salicin also works because it has similar anti-inflammatory properties to aspirin and is used in the production of acne products to relieve acne and other skin irritations.
Post time: Feb-15-2023