News - Can bitter melon extract reduce blood pressure？

what is bitter melon extract？

Bitter melon extract is derived from the fruit of Momordica charantia and is a natural ingredient widely used in traditional Chinese medicine and modern health care products. It has received attention for its efficacy in regulating blood sugar, promoting metabolic health, and boosting immunity. Bitter melon extract is rich in many bioactive ingredients and has multiple benefits to human health.

Main component

1. Saponins (Charantin)
• Has the effect of lowering blood sugar, is one of the important components of bitter melon extract.

2. Plant insulin (Polypeptide-p)
• An insulin-like compound of plant origin that helps regulate blood sugar levels.

3. Momordicosides
• Active ingredients with anti-inflammatory and antioxidant effects.

4. Vitamins and minerals
• High in vitamin C, vitamin A, potassium, and iron, which contributes to overall health.

5. Flavonoids
• Provides antioxidant effects and protects cells from free radical damage.

Lower Blood Sugar

The mechanism of action of bitter melon extract in lowering blood sugar mainly involves various physiological regulation, it can not only directly affect glucose metabolism, but also improve the effectiveness of insulin

1. Simulate insulin action
• Plant insulin (Polypeptide-p) :
• Bitter melon extract contains an insulin-like polypeptide compound, which can mimic the function of insulin and promote glucose into cells for energy, thereby reducing glucose concentration in the blood.
• It is especially suitable for patients with insufficient insulin secretion or impaired insulin function.

2. Increase insulin sensitivity
• Improve insulin resistance:
• The active ingredients in bitter melon, such as saponins (Charantin), can improve the cell's sensitivity to insulin by regulating the cell's insulin receptors, helping to absorb and use blood sugar more efficiently.
• For people with type 2 diabetes, insulin resistance is a major problem, and bitter melon extract can work by reducing this resistance.

3. Inhibit sugar absorption
• Reduces the absorption of glucose by the gut:
• Certain components of bitter melon extract can inhibit α-glucosidase activity in the gut. This enzyme is responsible for breaking down complex carbohydrates into glucose, and inhibiting its activity reduces the rate at which blood sugar rises, especially during post-meal peaks.

4. Regulate glucose metabolizing enzymes
• Bitter melon extract can:
Activate AMPK (AMP-activated protein kinase) : AMPK is a cellular energy regulatory switch that promotes the conversion of glucose to energy and reduces glucose production in the liver.
• Inhibits gluconeogenesis in the liver, reducing the liver's release of excessive glucose into the blood.

5. Anti-oxidation protects the pancreas
• Polyphenols and flavonoids in bitter melon extract have antioxidant effects and can protect pancreatic beta cells from oxidative stress.
• Beta cell health is essential for insulin secretion, and bitter melon extract can indirectly promote normal insulin secretion.

6. Reduce the impact of chronic inflammation on blood sugar
• The active ingredient in bitter melon can inhibit the release of inflammatory factors in the body, such as TNF-α, and chronic inflammation is closely related to insulin resistance.
• By reducing inflammation levels, bitter melon extract can improve overall glucose metabolism.